Sleep disorders and their determinants in multiple system atrophy.
نویسندگان
چکیده
OBJECTIVES To evaluate the incidence, types, determinants, and consequences of sleep disorders in patients with multiple system atrophy (MSA) and determine whether their characteristics are similar to those of patients with Parkinson's disease (PD). METHODS Information about sleep disorders was collected using a standardised questionnaire in an unselected group of 57 patients with MSA and in 62 patients with PD matched as a group for age, sex distribution, and disease duration. RESULTS Seventy percent of patients with MSA complained of sleep disorders compared with 51% of patients with PD (p=0.03). The most commonly reported sleep disorders were sleep fragmentation (52.5%), vocalisation (60%), REM sleep behaviour disorder (47.5%), and nocturnal stridor (19%). Except for sleep fragmentation, the incidence of these disorders was significantly higher than in PD. Sleep problems tended to be associated with more severe motor symptoms, longer disease duration, depression, and longer duration of levodopa treatment. Half of patients with MSA with sleep disorders complained of daytime somnolence compared with 30% of patients with PD. Daytime somnolence was significantly associated with disease severity in MSA. CONCLUSION This study shows that sleep disorders are more common in patients with MSA than in those with PD after the same duration of the disease, reflecting the more diffuse underlying pathological process in MSA.
منابع مشابه
Fatigue Severity and Sleep Disorders Among Patients With Multiple Sclerosis: A Cross-sectional Study From Iran
Background: Multiple sclerosis (MS) is the most prevalent autoimmune chronic disease globally. The current study was conducted to determine the relationship between fatigue severity and circadian rhythm sleep disorders among Iranian MS patients. Methods: The statistical population of this cross-sectional study included MS patients who were members of the MS Association in Khorramabad City, so...
متن کاملP 35: The Mediating Role of Meta-Cognitive Beliefs on the Cognitive-Executive Functions of Brain, Sleep Disorders, Optic Neuritis in Multiple Sclerosis Patients
Introduction: Multiple sclerosis (MS) is a chronic, autoimmune, and inflammatory nervous system disease. It leads to the loss of myelin in the white matter of brain, spinal cord and optic nerves. As a chronic disease with sudden and unpredictable Side effects and complications of the disease will lead to disability and dependency in life. Causes neurologic symptoms and sig. The purpose of the p...
متن کاملAuthor's response to reviews Title: Daytime sleepiness in Japanese patients with multiple system atrophy: prevalence and determinants Authors:
متن کامل
Visualizing Multiple System Atrophy Studies Based on Collaboration Network and Centrality Indices in Web of Science Database
Introduction: Social network analysis is an analytical method based on graph theories that identifies relationships between individuals or factors to analyze the social structures resulted from those relationships. The objective of this study was to analyze co-authorship and co-word networks based on scientometric indicators and centrality measures in the studies on multiple atrophy system dise...
متن کاملVisualizing Multiple System Atrophy Studies Based on Collaboration Network and Centrality Indices in Web of Science Database
Introduction: Social network analysis is an analytical method based on graph theories that identifies relationships between individuals or factors to analyze the social structures resulted from those relationships. The objective of this study was to analyze co-authorship and co-word networks based on scientometric indicators and centrality measures in the studies on multiple atrophy system dise...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Journal of neurology, neurosurgery, and psychiatry
دوره 72 6 شماره
صفحات -
تاریخ انتشار 2002